How environmental exposures and diabetes affect kidney health using molecular and genetic tools
Multi-Omics at the Intersections of Environment, Diabetes, and Kidney Disease: A Multi-Omics for Health and Disease Study Site
This project collects biological samples and environmental information from adults to learn how exposures and molecular markers relate to diabetes and worsening kidney disease, with emphasis on Black and Hispanic communities.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11195103 on NIH RePORTER |
What this research studies
We will enroll 300 adults (200 with diabetes, about half of whom have kidney disease, and 100 healthy controls) and follow them at the University of Illinois at Chicago site. Participants will provide blood, urine, and exposure information and undergo tests to measure genes, proteins, metabolites, and other molecular signals. The team will combine these 'multi-omics' data with environmental and social risk factors to look for patterns linked to diabetic kidney disease. This site is part of a larger consortium so findings can be compared across diverse populations to help explain higher risks in Black and Hispanic groups.
Who could benefit from this research
Good fit: Adults aged 21 and older with diabetes (including those with diabetic kidney disease) and healthy adult controls, with particular outreach to Black and Hispanic individuals.
Not a fit: People under 21, those not willing or able to attend clinic visits in the Chicago area, or those seeking immediate clinical treatment rather than research participation are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could identify biological and environmental signals that enable earlier detection, better prevention, or more targeted treatments for diabetic kidney disease in diverse populations.
How similar studies have performed: Prior studies have linked environmental exposures and some molecular markers to kidney disease, but combining broad multi-omics with environmental and social data in diverse populations is relatively new.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Kelly, Tanika Nicole — University of Illinois at Chicago
- Study coordinator: Kelly, Tanika Nicole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.