How environmental chemicals affect weight and bone health in teenagers

Environmental Chemicals, Adiposity, and Bone Accrual Across Adolescence

['FUNDING_R01'] · MAINEHEALTH · NIH-10558755

This study is looking at how certain chemicals found in the environment, like PFASs and phthalates, might affect weight and bone health in kids as they grow up, and it’s for adolescents who want to understand how these factors, along with their diet, could impact their overall health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMAINEHEALTH (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10558755 on ClinicalTrials.gov

What this research studies

This research investigates the impact of environmental chemicals, specifically PFASs and phthalates, on body weight and bone density during adolescence. By studying a cohort of children and tracking their health into late adolescence, the research aims to identify how these chemicals may contribute to obesity and low bone mineral density. The study will also consider dietary factors, which have not been thoroughly examined in previous research. Participants will undergo assessments to measure their exposure to these chemicals and their effects on body composition and bone health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who may be affected by obesity or bone health issues.

Not a fit: Patients outside the age range of 12 to 20 or those without concerns related to obesity or bone density may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies for obesity and osteoporosis in adolescents.

How similar studies have performed: Previous studies have shown promising results regarding the effects of environmental chemicals on health, but this research aims to explore these connections in a novel way by focusing on adolescents.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.