How environmental chemicals affect human health through specific receptors
Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and Morbidity
This study is looking at how your body reacts to certain chemicals in the environment and how that might affect your liver health and risk for diseases related to alcohol, with the goal of finding new ways to help you stay healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11109519 on NIH RePORTER |
What this research studies
This research investigates how certain receptors in the body respond to environmental chemicals and their role in the development of chronic diseases, particularly those related to alcohol and liver health. By studying these receptors, the research aims to understand how environmental factors contribute to conditions like alcoholic liver disease and metabolic syndrome. The approach includes analyzing the metabolism of both harmful substances and natural compounds in the body, which could lead to new strategies for prevention and treatment. Patients may benefit from insights that could inform lifestyle changes or therapeutic interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for or suffering from alcohol-related liver diseases and other chronic conditions influenced by environmental factors.
Not a fit: Patients with liver diseases not related to environmental exposures or alcohol may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new prevention and treatment strategies for chronic diseases linked to environmental exposures.
How similar studies have performed: Previous research has shown promising results in understanding the role of xenobiotic receptors in disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Xie, Wen — University of Pittsburgh at Pittsburgh
- Study coordinator: Xie, Wen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.