How environmental chemicals affect gut bacteria and health

Environmental Chemical Impact on the Host-Microbiome Interaction

NIH-funded research Pennsylvania State University, the · NIH-11096080

This study looks at how chemicals in our environment can affect the good bacteria in our gut and how that might lead to health problems later on, especially in young mice, to help us understand better how these chemicals impact our health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-11096080 on NIH RePORTER

What this research studies

This research investigates the impact of environmental chemicals on the gut microbiota and how these interactions influence health outcomes. By using mouse models, the study aims to understand how early-life exposure to these chemicals can lead to metabolic disorders and inflammatory diseases later in life. The research will explore the mechanisms by which gut bacteria respond to chemical exposure and how this affects the host's health. The findings could provide valuable insights for improving risk assessments related to chemical exposure.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with a history of exposure to environmental chemicals or those suffering from metabolic or inflammatory disorders.

Not a fit: Patients who have no history of chemical exposure or do not suffer from related health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of diseases linked to environmental chemical exposure.

How similar studies have performed: Previous research has shown promising results in understanding the role of gut microbiota in health, suggesting that this approach could yield significant insights.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.