How environmental chemicals affect gut bacteria and health
Official title: Environmental Chemical Impact on the Host-Microbiome Interaction
Funded at Pennsylvania State University, the · NIH-11096080 · Data updated 2026-11-12
This study looks at how chemicals in our environment can affect the good bacteria in our gut and how that might lead to health problems later on, especially in young mice, to help us understand better how these chemicals impact our health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | June 13, 2023 |
| Project end | May 31, 2031 |
| Funding year | 2025 |
| Award (this year) | $901,338 |
| NIH project number | 5R35ES035027-03 |
| Project ID | NIH-11096080 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of exposure to environmental chemicals or those suffering from metabolic or inflammatory disorders.
✕Less likely to help
Patients who have no history of chemical exposure or do not suffer from related health conditions may not benefit from this research.
What this research studies
This research investigates the impact of environmental chemicals on the gut microbiota and how these interactions influence health outcomes. By using mouse models, the study aims to understand how early-life exposure to these chemicals can lead to metabolic disorders and inflammatory diseases later in life. The research will explore the mechanisms by which gut bacteria respond to chemical exposure and how this affects the host's health. The findings could provide valuable insights for improving risk assessments related to chemical exposure.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of diseases linked to environmental chemical exposure.
How similar studies have gone: Previous research has shown promising results in understanding the role of gut microbiota in health, suggesting that this approach could yield significant insights.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Patterson, Andrew — Pennsylvania State University, the
- Study coordinator: Patterson, Andrew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.