How environmental challenges affect aging in dogs' immune systems

Effects of environmental adversity on molecular aging in the immune system of companion dogs

NIH-funded research Arizona State University-Tempe Campus · NIH-10973362

This study looks at how different challenges in a dog's environment affect their immune system as they age, and it aims to help us understand how to keep our furry friends healthier for longer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus NIH-funded
Lab location1 site (Tempe, United States)
Project IDNIH-10973362 on NIH RePORTER

What this research studies

This research investigates how different environmental adversities impact the aging process in the immune systems of companion dogs. By analyzing a cohort of 1,000 dogs, the study aims to uncover the relationship between environmental factors and molecular aging, particularly focusing on DNA methylation changes. The findings could provide insights into how these factors accelerate aging and influence health and lifespan in dogs, which may also have implications for understanding aging in humans. The research will also explore the potential for developing strategies to promote healthier aging experiences.

Who could benefit from this research

Good fit: Ideal candidates for this research are companion dogs that have experienced various environmental adversities.

Not a fit: Dogs that have not faced significant environmental challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health and longevity for dogs by identifying environmental factors that contribute to accelerated aging.

How similar studies have performed: Other research has shown promising results in understanding the effects of environmental factors on aging, making this approach both relevant and potentially impactful.

Where this research is happening

Tempe, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.