NIH-funded research NIH-funded research

How environmental challenges affect aging in dogs' immune systems

Official title: Effects of environmental adversity on molecular aging in the immune system of companion dogs

Funded at Arizona State University-Tempe Campus · NIH-10973362 · Data updated 2026-11-12

This study looks at how different challenges in a dog's environment affect their immune system as they age, and it aims to help us understand how to keep our furry friends healthier for longer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus
NIH-funded
Lab location1 site (Tempe, United States)
Project startAugust 26, 2024
Project endAugust 25, 2026
Funding year2024
Award (this year)$50,474
NIH project number1F99AG088576-01
Project IDNIH-10973362 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are companion dogs that have experienced various environmental adversities.

Less likely to help

Dogs that have not faced significant environmental challenges may not benefit from this research.

What this research studies

This research investigates how different environmental adversities impact the aging process in the immune systems of companion dogs. By analyzing a cohort of 1,000 dogs, the study aims to uncover the relationship between environmental factors and molecular aging, particularly focusing on DNA methylation changes. The findings could provide insights into how these factors accelerate aging and influence health and lifespan in dogs, which may also have implications for understanding aging in humans. The research will also explore the potential for developing strategies to promote healthier aging experiences.

Why it matters

Potential benefit: If successful, this research could lead to improved health and longevity for dogs by identifying environmental factors that contribute to accelerated aging.

How similar studies have gone: Other research has shown promising results in understanding the effects of environmental factors on aging, making this approach both relevant and potentially impactful.

Where this research is happening

  • Arizona State University-Tempe Campus
    Tempe, United States
    Active

Researchers

  • Principal investigator: Mccoy, Brianah — Arizona State University-Tempe Campus
  • Study coordinator: Mccoy, Brianah

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.