NIH-funded research R01 grant

How Emotions and Aging Affect Health Choices

Official title: Emotion, Aging, and Decision Making

Funded at De Paul University · NIH-11075860 · Data updated 2026-11-12

This project explores how feelings and social connections help older adults make healthy choices, especially regarding exercise, and how this might relate to dementia risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDe Paul University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 30, 2014
Project endFebruary 29, 2028
Funding year2025
Award (this year)$539,841
NIH project number5R01AG043533-09
Project IDNIH-11075860 on NIH RePORTER

Who could benefit from this research

Could help

This research is relevant to older adults, particularly those interested in understanding how emotions and social connections influence their health decisions and physical activity, especially if they have a genetic risk for dementia.

Less likely to help

Patients who are not older adults or those not interested in the psychological aspects of health decision-making may not directly benefit from this specific research.

What this research studies

This project explores how our emotions and social interactions guide the health decisions we make as we get older. Researchers are particularly interested in how positive feelings, especially when shared with others, can encourage older adults to be more physically active. They will also consider how genetic factors, like the APOE e4 gene linked to Alzheimer's disease, might influence the health benefits older adults get from exercise. The goal is to understand how to best support healthy behaviors in later life to promote overall well-being.

Why it matters

Potential benefit: If successful, this work could lead to new ways to encourage older adults to make healthier choices and stay active, potentially helping to maintain cognitive and physical health.

How similar studies have gone: Previous work by the researchers has shown that positive emotions and social goals can motivate older adults to exercise, suggesting a foundation for this approach.

Where this research is happening

  • De Paul University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Mikels, Joseph a — De Paul University
  • Study coordinator: Mikels, Joseph a

Related research

Other NIH-funded projects on the same topics.

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  • Understanding decision-making in aging and Alzheimer's disease

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  • Understanding how older adults with Alzheimer's make decisions about living at home

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  • Understanding how octopuses integrate sensory information and make decisions

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.