NIH-funded research R01 grant

How emotion-related brain circuits shape new mothers' caregiving

Official title: The Role of Corticolimbic Circuits in Maternal Behavior

Funded at Rutgers, the State Univ of N.j. · NIH-11361778 · Data updated 2026-11-12

This research looks at how changes in emotion-related brain circuits after childbirth affect mothers' stress responses and caregiving.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j.
NIH-funded
Lab location1 site (Piscataway, United States)
Project startAugust 1, 2024
Project endJuly 31, 2029
Funding year2025
Award (this year)$56,564
NIH project number3R01HD113761-02S1
Project IDNIH-11361778 on NIH RePORTER

Who could benefit from this research

Could help

New mothers or people who recently gave birth who are experiencing high stress, anxiety, or difficulties with bonding would be most directly relevant to this research.

Less likely to help

People who are not pregnant or postpartum, or whose health issues are unrelated to stress, emotion, or caregiving, are unlikely to benefit directly from this project.

What this research studies

This project studies how corticolimbic (emotion and stress) brain regions interact with core maternal brain areas after childbirth. Researchers will use genetic tools and neural-circuit mapping in lab models to trace specific neuron populations and measure changes in synaptic function and gene activity. They will link those brain changes to behaviors related to maternal care, threat responses, and stress handling. Findings are intended to reveal biological mechanisms that could guide future ways to support mothers' emotional health and parenting.

Why it matters

Potential benefit: If successful, this work could point to new approaches to help mothers manage stress and strengthen bonding with their infants.

How similar studies have gone: Animal and clinical studies have suggested links between corticolimbic circuits and maternal mood or caregiving, but applying circuit-level discoveries to human therapies remains early-stage.

Where this research is happening

  • Rutgers, the State Univ of N.j.
    Piscataway, United States
    Active

Researchers

  • Principal investigator: Shumyatsky, Gleb P — Rutgers, the State Univ of N.j.
  • Study coordinator: Shumyatsky, Gleb P

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.