How embryos control their cell growth and division
Official title: Mechanisms of cell cycle regulation in embryos of normal and unusual size
Funded at Princeton University · NIH-10995403 · Data updated 2026-11-12
This study looks at how mouse embryos control their cell numbers during early development, especially when they have twice as many cells as usual, to learn more about how cells grow and organize, which could help us understand more about development and reproductive health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | November 1, 2024 |
| Project end | October 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $32,974 |
| NIH project number | 1F31HD115409-01A1 |
| Project ID | NIH-10995403 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals undergoing fertility treatments or those interested in understanding embryonic development.
✕Less likely to help
Patients with established pregnancies or those not seeking fertility assistance may not benefit directly from this research.
What this research studies
This research investigates how embryos manage their cell numbers during early development, particularly focusing on mouse embryos. By observing embryos that have double the normal number of cells, the study aims to understand the mechanisms behind cell cycle regulation and how abnormalities in cell organization can affect this process. Using advanced imaging techniques and fluorescent markers, researchers will explore the relationship between cell cycle dynamics and the physical structure of the embryo. This work could provide insights into fundamental developmental biology and potential implications for reproductive health.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of embryonic development and lead to improved strategies for addressing developmental disorders.
How similar studies have gone: Previous research has shown promising results in understanding cell cycle regulation in embryos, indicating that this approach could yield valuable insights.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Bernys, Alana Catherine — Princeton University
- Study coordinator: Bernys, Alana Catherine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.