How electronic nicotine delivery systems affect gum health

Early Periodontal Health Impacts of Electronic Nicotine Delivery System (ENDS) Usage

NIH-funded research Underwriters Laboratories INC. · NIH-10691174

This study is looking at how using e-cigarettes might affect your gum health and increase the risk of gum disease, and it's inviting people who use these devices to help us understand the early signs of oral health problems related to them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUnderwriters Laboratories INC. NIH-funded
Lab location1 site (Northbrook, United States)
Project IDNIH-10691174 on NIH RePORTER

What this research studies

This research investigates the impact of electronic nicotine delivery systems (ENDS) on oral health, particularly focusing on gum inflammation and the risk of periodontal disease. By examining the behaviors and exposures associated with ENDS usage, the study aims to identify early indicators of oral health issues linked to these devices. The research will involve recruiting participants who use ENDS and assessing their oral health to understand the biological responses and mechanisms that contribute to disease. This comprehensive approach seeks to develop strategies for preventing gum disease related to ENDS usage.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who are current exclusive users of electronic nicotine delivery systems or those who have never used tobacco products.

Not a fit: Patients who do not use electronic nicotine delivery systems or traditional tobacco products may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies for periodontal disease in users of electronic nicotine delivery systems.

How similar studies have performed: While the specific focus on ENDS and periodontal health is relatively novel, there is existing research indicating that tobacco use negatively impacts oral health, suggesting potential for success in this area.

Where this research is happening

Northbrook, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorderDisease susceptibilityliability to disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.