How electronic cigarette exposure affects blood vessel health
Official title: Xanthine oxidase mediates the vascular dysfunction with direct and in-utero electronic cigarette exposure
Funded at West Virginia University · NIH-11141321 · Data updated 2026-11-12
This study looks at how using electronic cigarettes affects heart and blood vessel health, especially for young adults and pregnant women, to help us understand the long-term risks of vaping.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $619,477 |
| NIH project number | 1R56ES035719-01A1 |
| Project ID | NIH-11141321 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include young adults who use electronic cigarettes and pregnant women who vape.
✕Less likely to help
Patients who do not use electronic cigarettes or are not exposed to vaping during pregnancy may not benefit from this research.
What this research studies
This research investigates the impact of electronic cigarette (Ecig) exposure on vascular health, particularly focusing on both direct exposure and exposure during pregnancy. The study aims to understand how Ecig usage, especially among young adults and pregnant women, leads to negative effects on blood vessels and overall cardiovascular health. By using animal models, the researchers will explore the mechanisms behind these adverse effects and how they may persist into adulthood. This research is crucial for understanding the long-term health implications of Ecig use.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for vascular dysfunction related to electronic cigarette use.
How similar studies have gone: Previous studies have indicated negative health outcomes associated with electronic cigarette use, suggesting that this research builds on established findings rather than exploring a completely novel area.
Where this research is happening
-
West Virginia University
Morgantown, United States Active
Researchers
- Principal investigator: Chantler, Paul D — West Virginia University
- Study coordinator: Chantler, Paul D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.