How elastic parts of muscles help movement

Elastic mechanisms in locomotion

NIH-funded research Brown University · NIH-11245718

This project looks at how elastic parts inside muscles change the strength, speed, and power of movement for people with aging-related weakness or movement problems after stroke or cerebral palsy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrown University NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11245718 on NIH RePORTER

What this research studies

You would hear that researchers are combining experiments on animal muscles, physical models, and three-dimensional computer models to understand how internal elastic elements, fluid pressure, and contracting fibers work together. They measure muscle force, speed, and power in different animal systems and build 3-D physical and computational models to capture multi-scale interactions. Specific tests include whether fluid forces add to muscle output and whether stiffer connective tissue in older muscle reduces force and work. The goal is to link these basic mechanics to walking and other movement problems to guide future treatments or rehab strategies.

Who could benefit from this research

Good fit: Ideal candidates are people with age-related muscle weakness or gait problems after stroke or cerebral palsy who are interested in contributing to research on movement mechanics.

Not a fit: People with conditions unrelated to muscle mechanics (for example, primarily cognitive disorders) or those seeking immediate clinical treatments are unlikely to receive direct benefit from this basic-mechanics project.

Why it matters

Potential benefit: If successful, this work could point to new ways to improve strength, speed, or walking in older adults and people recovering from stroke or cerebral palsy.

How similar studies have performed: Previous lab and animal studies show three-dimensional muscle interactions matter, but combining physical models, animal experiments, and multi-scale 3-D modeling to link elastic elements to gait is relatively novel.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.