How economic and policy changes affect opioid use disorder

Economic Conditions, Policy Environments, and Opioid Use Disorder

NIH-funded research University of Rochester · NIH-11094715

This project looks at how job loss, business and school closures, and pandemic-era policies changed opioid use, overdoses, and access to treatment for people with or at risk of opioid use disorder.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11094715 on NIH RePORTER

What this research studies

From a patient perspective, the researchers use a large set of insurance claims and electronic health records covering about half of the U.S. from 2018 through 2025 to track opioid use, overdoses, and treatments such as buprenorphine. They link those health records to local economic and policy changes — like unemployment, stimulus payments, expanded Medicaid coverage, eviction moratoria, and school or business closures — to see how those shifts coincided with opioid-related outcomes. The team compares different communities and age groups, including children, adolescents, and adults, to identify who was helped or harmed by these changes. Results aim to point to policies that improved or reduced access to medication for opioid use disorder so future decisions can better protect people.

Who could benefit from this research

Good fit: The research uses records from people with opioid use, overdose events, or opioid treatment in claims and EHR data between 2018 and 2025, including adolescents and adults.

Not a fit: People who do not appear in the examined claims or EHR databases, those outside the covered regions, or those seeking immediate clinical care will not directly benefit from this analysis.

Why it matters

Potential benefit: If successful, this work could guide policy and health-system changes that reduce overdoses and improve access to lifesaving treatments like buprenorphine.

How similar studies have performed: Previous studies have linked economic hardship to increases in opioid use and overdoses, but this linked national claims and EHR approach is a larger and more comprehensive effort.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.