NIH-funded research R21 grant

How early resource scarcity affects addiction behaviors in adolescents

Official title: Determining the effect of early resource scarcity on adolescent addiction-related behavior and cell-type specific transcription

Funded at Georgia State University · NIH-10934371 · Data updated 2026-11-12

This study looks at how growing up with fewer resources can affect young people's choices and behaviors related to addiction, using rats to see how it impacts their brains and their use of opioids, which could help us find ways to prevent substance use problems in the future.

More Addiction research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionGeorgia State University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startSeptember 30, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$199,270
NIH project number5R21DA059966-02
Project IDNIH-10934371 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents who have experienced early life trauma or resource scarcity.

Less likely to help

Patients who have not experienced early life trauma or resource scarcity may not benefit from this research.

What this research studies

This research investigates how early life experiences, specifically resource scarcity, influence addiction-related behaviors during adolescence. Using a rat model, the study examines the effects of limited resources on impulsivity and opioid consumption, focusing on changes in brain function in the medial prefrontal cortex. By comparing rats raised in low-resource environments to those in adequate conditions, the research aims to uncover critical insights into the development of substance use disorders and potential early interventions.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for substance use disorders in adolescents.

How similar studies have gone: Previous research has shown that early life experiences significantly impact addiction behaviors, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Georgia State University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Bangasser, Debra a — Georgia State University
  • Study coordinator: Bangasser, Debra a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.