How early life trauma affects aging in animals similar to humans
Early life trauma and aging using a long-lived animal model
This study looks at how tough experiences in childhood can affect health as elephants get older, helping us learn more about how similar issues might impact humans too, with the hope of finding ways to improve health for everyone as they age.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-11002271 on NIH RePORTER |
What this research studies
This research investigates the impact of adverse childhood experiences (ACEs) on aging and health outcomes in a long-lived animal model, specifically elephants. By studying the similarities between elephants and humans, the research aims to understand how early trauma can lead to increased risks of diseases such as obesity, cancer, and diabetes in adulthood. The approach includes developing expertise in psychobiology and behavior, enhancing skills in aging science, and designing randomized experiments to gather meaningful data. The ultimate goal is to identify interventions that can help mitigate the negative effects of ACEs on health as individuals age.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced adverse childhood experiences and are at risk for age-related diseases.
Not a fit: Patients who have not experienced any adverse childhood experiences may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new interventions that improve health outcomes and longevity for individuals who have experienced early life trauma.
How similar studies have performed: Previous research has shown promising results in understanding the effects of early life trauma on health, but this specific approach using elephants as a model is relatively novel.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Chusyd, Daniella E. — Trustees of Indiana University
- Study coordinator: Chusyd, Daniella E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.