How early life stress affects heart disease risk and resilience
Official title: Early Life Stress Induced Mechanisms of Cardiovascular Disease Risk and Resilience
Funded at University of Alabama at Birmingham · NIH-11010882 · Data updated 2026-11-12
This study is looking at how tough experiences in childhood, like abuse or neglect, might affect heart health as people grow older, and it hopes to find ways to prevent or treat heart problems for those who have faced these challenges.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | February 15, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $2,012,602 |
| NIH project number | 5P01HL158500-03 |
| Project ID | NIH-11010882 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced significant early life stress, such as abuse or neglect, and are at risk for cardiovascular disease.
✕Less likely to help
Patients who have not experienced early life stress or who do not have cardiovascular disease risk factors may not benefit from this research.
What this research studies
This research investigates the impact of early life stress, such as abuse or neglect, on the risk of developing cardiovascular disease later in life. It aims to understand the biological mechanisms that link these stressful experiences to heart health issues. By studying individuals who have experienced early life stress, the research seeks to identify potential prevention and treatment strategies for cardiovascular problems. The project will utilize a combination of clinical assessments and advanced scientific techniques to gather data.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cardiovascular disease in individuals who have experienced early life stress.
How similar studies have gone: Previous research has established a link between early life stress and cardiovascular disease, suggesting that this approach has potential for significant insights and advancements.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Pollock, Jennifer S — University of Alabama at Birmingham
- Study coordinator: Pollock, Jennifer S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.