How early life stress affects heart disease risk and resilience

Early Life Stress Induced Mechanisms of Cardiovascular Disease Risk and Resilience

NIH-funded research University of Alabama at Birmingham · NIH-11010882

This study is looking at how tough experiences in childhood, like abuse or neglect, might affect heart health as people grow older, and it hopes to find ways to prevent or treat heart problems for those who have faced these challenges.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11010882 on NIH RePORTER

What this research studies

This research investigates the impact of early life stress, such as abuse or neglect, on the risk of developing cardiovascular disease later in life. It aims to understand the biological mechanisms that link these stressful experiences to heart health issues. By studying individuals who have experienced early life stress, the research seeks to identify potential prevention and treatment strategies for cardiovascular problems. The project will utilize a combination of clinical assessments and advanced scientific techniques to gather data.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced significant early life stress, such as abuse or neglect, and are at risk for cardiovascular disease.

Not a fit: Patients who have not experienced early life stress or who do not have cardiovascular disease risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cardiovascular disease in individuals who have experienced early life stress.

How similar studies have performed: Previous research has established a link between early life stress and cardiovascular disease, suggesting that this approach has potential for significant insights and advancements.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.