How early life gut bacteria affect asthma risk in children
Microbiome Influences on Asthma-Related Outcomes in Early Life
This study looks at how the bacteria in babies' tummies might affect their chances of getting asthma, especially by comparing kids from different places like Tucson and Nogales, and it explores how things like living on a farm or having pets can help shape those bacteria to potentially protect against asthma.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10932533 on NIH RePORTER |
What this research studies
This research investigates how the gut microbiome in infants influences the risk of developing asthma, particularly focusing on children from different environments. It examines how early exposures, such as living on farms or having pets, can shape the gut bacteria and immune responses of newborns. By comparing children from Tucson, Arizona, and Nogales, Mexico, the study aims to identify specific microbial factors that may protect against asthma. The research involves analyzing the gut microbiota and immune development in infants to understand their relationship with asthma outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children, particularly those living in Tucson, Arizona, or Nogales, Mexico.
Not a fit: Patients who are older than 11 years or those without a family history of asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing asthma in children by promoting beneficial gut bacteria.
How similar studies have performed: Previous research has shown promising results in understanding the role of the microbiome in asthma, making this approach both relevant and potentially impactful.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Martinez, Fernando D — University of Arizona
- Study coordinator: Martinez, Fernando D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.