How early life factors and diet affect breast cancer risk
Lifestyle associated reactive metabolites and their negative impact on breast cancer risk
This study looks at how things that happen during puberty, like sugar intake and environmental factors, can affect breast tissue development and potentially increase the risk of breast cancer, with the hope of finding ways to lower that risk in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10875268 on NIH RePORTER |
What this research studies
This research investigates how factors during early life, particularly during puberty, influence the development of breast tissue and the subsequent risk of breast cancer. It focuses on the role of advanced glycation end products (AGEs), which are harmful metabolites produced from sugar consumption and environmental factors. By studying these effects in animal models, the research aims to uncover the biological mechanisms that lead to abnormal breast development and cancer risk. The ultimate goal is to identify strategies that could help reduce the burden of breast cancer in the future.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of breast cancer or those concerned about their breast cancer risk due to lifestyle factors.
Not a fit: Patients who are already diagnosed with advanced breast cancer may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing breast cancer by understanding and mitigating the effects of early life factors and diet.
How similar studies have performed: Other research has shown promising results in understanding the impact of diet and early life factors on cancer risk, suggesting that this approach could yield valuable insights.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Findlay, Victoria Jane — Virginia Commonwealth University
- Study coordinator: Findlay, Victoria Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.