How early-life challenges affect health and obesity in Mexican American children
Common and Distinct Influences of Prenatal and Postnatal Early-Life Adversity on Epigenomic Trajectories in Mexican American Children
This study looks at how tough experiences early in life can affect the health of Mexican American kids, especially when it comes to obesity, and aims to find ways to predict and prevent these health issues in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10808182 on NIH RePORTER |
What this research studies
This research investigates the impact of early-life adversity on the health trajectories of Mexican American children, particularly focusing on obesity. It examines how factors like prenatal and postnatal stressors influence changes in DNA methylation and gene expression over time. By analyzing biological samples and data, the study aims to understand the long-term effects of these adversities on children's health and development. The goal is to identify potential biomarkers that could help in predicting and preventing obesity and related health disparities.
Who could benefit from this research
Good fit: Ideal candidates for this research are Mexican American children aged 0-20 who have experienced early-life adversities.
Not a fit: Patients who do not identify as Mexican American or who have not experienced early-life adversities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for obesity and health disparities in children.
How similar studies have performed: Previous research has shown promising results in understanding the link between early-life adversity and health outcomes, but this study aims to explore new methodologies and longitudinal data.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Deardorff, Julianna — University of California Berkeley
- Study coordinator: Deardorff, Julianna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.