How early life and environmental factors affect kidney function
Developmental Origins of Kidney Function in Early Life and Environmental Risks
This study is looking at how kidney health develops in young children, especially those with chronic kidney disease, and how things like pesticides and chemicals in our environment might affect their kidneys during pregnancy and early life, with the goal of finding ways to improve kidney health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10878943 on NIH RePORTER |
What this research studies
This research investigates how kidney function develops in early life and the impact of environmental risks, particularly exposure to synthetic chemicals like pesticides and phthalates. By studying children with chronic kidney disease (CKD), the research aims to understand how these environmental factors may disrupt kidney development during pregnancy and infancy. The team will analyze the effects of various chemicals on kidney health and oxidative stress, providing insights into the origins of CKD. This study seeks to identify modifiable risks that could improve kidney health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include children under 11 years old who may be exposed to environmental chemicals and have a family history of kidney issues.
Not a fit: Patients with pre-existing severe kidney disease or those not exposed to the identified environmental risks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for chronic kidney disease in children and adults.
How similar studies have performed: Previous studies have shown a correlation between environmental chemical exposure and kidney function decline, suggesting that this research builds on established findings.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Trasande, Leonardo — New York University School of Medicine
- Study coordinator: Trasande, Leonardo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.