How early exposure to household air pollution affects heart health in children

Early life household air pollution, metal composition and cardiovascular health: Evidence from GRAPHS

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11201348

This study looks at how smoke from cooking fires can affect kids' heart health from before they are born until they turn 12, helping us understand the risks and find ways to keep them safe.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11201348 on NIH RePORTER

What this research studies

This research investigates the impact of household air pollution (HAP) on cardiovascular health in children from prenatal stages to age 12. It focuses on how exposure to smoke from cooking fires and the metal composition of this pollution can alter heart development and increase the risk of cardiovascular diseases later in life. By utilizing data from a pregnancy cohort in Ghana, the study aims to establish a clearer understanding of these health risks and identify potential interventions to reduce exposure. The research employs validated methodologies to assess cardiovascular outcomes in affected children.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0 to 12 years who have been exposed to household air pollution, particularly in low- and middle-income countries.

Not a fit: Patients who are not exposed to household air pollution or who are older than 12 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective strategies for reducing cardiovascular disease risk in children exposed to household air pollution.

How similar studies have performed: Previous research has shown significant health impacts from household air pollution, indicating that this approach is grounded in established findings.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorder
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.