How early exposure to household air pollution affects heart health in children

Early life household air pollution, metal composition and cardiovascular health: Evidence from GRAPHS

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10880610

This study is looking at how smoke from cooking fires affects the heart health of children from before they are born until they turn 12, to help find ways to reduce this pollution and keep kids healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10880610 on NIH RePORTER

What this research studies

This research investigates the impact of household air pollution (HAP) on cardiovascular health in children from prenatal stages to age 12. It focuses on understanding how exposure to smoke from cooking fires and the metal composition of this pollution can alter heart development and increase the risk of cardiovascular diseases later in life. The study builds on an existing pregnancy cohort in Ghana, using validated methods to assess health outcomes related to air pollution exposure. By identifying these effects, the research aims to inform cost-effective interventions to reduce HAP exposure and improve child health.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0 to 12 years who have been exposed to household air pollution.

Not a fit: Patients who are not exposed to household air pollution or are older than 12 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular health in children and reduce the risk of heart disease in adulthood.

How similar studies have performed: Previous research has shown significant links between air pollution exposure and cardiovascular health, supporting the relevance of this study's approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.