How early eczema may lead to allergies and asthma in Black and White children
Refining the Atopic March: Mechanisms of Progression in Black and White Children
This project follows young Black and White children with early eczema to track who develops food allergies, asthma, or hay fever.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11103186 on NIH RePORTER |
What this research studies
Your child would join a long-term study that follows kids from early life who have atopic dermatitis (eczema). The team collects medical history, allergy testing, and regular clinic visits over time to watch how eczema, food allergy, asthma, and allergic rhinitis develop. This cohort includes a majority of Black children to understand differences between Black and White children. Researchers compare timing, combinations of allergic conditions, and biological markers to refine the idea of the 'atopic march.'
Who could benefit from this research
Good fit: Ideal candidates are young children (infancy through about 11 years) with early-life atopic dermatitis, including both Black and White children.
Not a fit: Children without eczema or those whose symptoms are due to non-allergic causes are unlikely to benefit directly from this study.
Why it matters
Potential benefit: If successful, this work could help doctors identify children at higher risk earlier and guide prevention or tailored care to reduce asthma and other allergies.
How similar studies have performed: Earlier cohorts mostly enrolled White children and showed that the classic atopic march applies to only a small fraction of children, so this racially diverse cohort is a relatively novel approach.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Khurana Hershey, Gurjit K. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Khurana Hershey, Gurjit K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.