NIH-funded research R03 grant

How early childhood support shapes health and family outcomes across generations

Official title: Demographic, Mortality, and Intergenerational Effects of Family Support Programs

Funded at De Paul University · NIH-11456839 · Data updated 2026-11-12

This project studies how a historical program that supported poor families in early childhood could influence health, births, and lifespan for people and their children many decades later.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionDe Paul University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 1, 2025
Project endAugust 31, 2027
Funding year2025
Award (this year)$161,814
NIH project number7R03HD117092-02
Project IDNIH-11456839 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable as this is a historical-data study using archival records, not recruiting living participants.

Less likely to help

No direct patient participation or benefit is expected since this uses historical records rather than enrolling people.

What this research studies

Researchers will analyze historical census data from England and Wales to see if changes in family support during childhood affected fertility and age at death across three generations. The study uses a natural historical experiment based on the Poor Law Amendment Act of 1834 to observe long-term outcomes. The project focuses on long-run health and longevity questions that matter to families today and will require careful handling of historical records and complex statistical analysis. The work could reveal how early-life conditions shape life trajectories for individuals and their descendants.

Why it matters

Potential benefit: If successful, the project could illuminate how early social supports influence long-term health and family outcomes, informing policies that invest in children.

How similar studies have gone: Previous work shows that early-life conditions influence later outcomes, but this project extends evidence across multiple generations using a novel historical natural experiment.

Where this research is happening

  • De Paul University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Mayo, Jennifer — De Paul University
  • Study coordinator: Mayo, Jennifer

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.