How early brain development affects aggressive and impulsive behavior
Official title: Developmental Origins of Aggressive and Impulsive Behavior
Funded at New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-11018566 · Data updated 2026-11-12
This study looks at how the brain develops during teenage years and how that affects aggressive and impulsive behaviors, hoping to find new ways to help people manage these traits by understanding the role of certain brain chemicals.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | March 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $660,930 |
| NIH project number | 5R01MH132911-03 |
| Project ID | NIH-11018566 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include adolescents and adults who exhibit aggressive or impulsive behaviors.
✕Less likely to help
Patients with no history of aggression or impulsivity may not receive benefit from this research.
What this research studies
This research investigates the biological mechanisms behind aggressive and impulsive behaviors, focusing on how brain development during adolescence influences these traits. By studying the roles of neurotransmitters like dopamine and serotonin, the research aims to understand how these chemicals affect brain circuits related to aggression. The study uses animal models to explore how changes in these neurotransmitters during critical developmental periods can lead to increased aggression and impulsivity in adulthood. Patients may benefit from insights that could lead to new treatments for managing aggressive behaviors.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating aggressive and impulsive behaviors in individuals.
How similar studies have gone: Previous research has shown promising results in understanding the role of neurotransmitters in aggression, suggesting that this approach could yield valuable insights.
Where this research is happening
-
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
New York, United States Active
Researchers
- Principal investigator: Ansorge, Mark Sascha — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Ansorge, Mark Sascha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.