How early and later life events affect thinking and dementia in older adults in China

Influences of Early and Later Life Events on Cognition and All-Cause Dementia in China

NIH-funded research University of Southern California · NIH-10899634

This study looks at how different life experiences and choices can affect brain health and the chances of developing dementia, especially Alzheimer's, in older adults in China, to help find ways to prevent cognitive decline.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10899634 on NIH RePORTER

What this research studies

This research investigates how various life events and factors throughout a person's life can influence cognitive health and the risk of developing dementia, particularly Alzheimer's disease, in older adults in China. By examining both early and later life experiences, including lifestyle choices and environmental influences, the study aims to identify protective and risk factors that contribute to cognitive decline. The researchers will utilize a life-course model to analyze data from different stages of life, focusing on aspects such as health conditions, social interactions, and socioeconomic status. This comprehensive approach seeks to enhance our understanding of dementia risk and inform future prevention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults living in China, particularly those with a family history of dementia or related cognitive issues.

Not a fit: Patients who are younger than 21 years old or those not residing in China may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline and dementia in older adults.

How similar studies have performed: Previous studies have shown success in identifying risk factors for dementia using similar life-course approaches, indicating that this research builds on established findings.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.