How drugs affect sleep and vice versa
Official title: Mechanisms of psychostimulant-sleep interactions
Funded at University of Utah · NIH-11222586 · Data updated 2026-11-12
This study is looking at how using drugs can mess with your sleep, even after you stop using them, and it aims to find out why this happens so that we can help people with both sleep problems and substance use issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | June 1, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $458,452 |
| NIH project number | 1R01DA061298-01A1 |
| Project ID | NIH-11222586 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of substance use disorders who are experiencing sleep disturbances.
✕Less likely to help
Patients who do not have substance use disorders or significant sleep issues may not benefit from this research.
What this research studies
This research investigates the complex relationship between substance use disorders and sleep disturbances. It aims to understand how repeated exposure to addictive substances alters sleep patterns, leading to issues like insomnia even during abstinence. The study will explore the neurobiological mechanisms involved and identify specific genes that influence these sleep irregularities. By examining both the effects of drugs on sleep and how sleep disturbances can contribute to substance use, the research seeks to uncover potential targets for treatment.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals struggling with substance use disorders by addressing their sleep-related issues.
How similar studies have gone: Previous research has shown that addressing sleep disturbances can improve outcomes for patients with substance use disorders, indicating that this approach has potential for success.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Rothenfluh, Adrian — University of Utah
- Study coordinator: Rothenfluh, Adrian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.