NIH-funded research R01 grant

How drinking water before meals affects weight control in older adults

Official title: Water Intake and Weight Control in Older Adults

Funded at Virginia Polytechnic Inst and St Univ · NIH-11019722 · Data updated 2026-11-12

This study is looking at how drinking different amounts of water can help adults over 50 who are overweight or obese manage their weight better, and it involves tracking your water intake to see how it affects your hunger and feelings of fullness.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Polytechnic Inst and St Univ
NIH-funded
Lab location1 site (Blacksburg, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$598,545
NIH project number5R01DK135410-03
Project IDNIH-11019722 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 50 and older who are overweight or obese.

Less likely to help

Patients who are under 50 years old or those with normal weight may not benefit from this research.

What this research studies

This research investigates the impact of water consumption on weight management in adults aged 50 and older who are overweight or obese. Participants will be assigned to one of three groups: one will drink 500 ml of water before each meal, another will consume 1500 ml of water throughout the day, and the third will follow a diet without specific water instructions. The study will use smart water bottles to track water intake and measure various indicators to assess compliance and effectiveness. By examining changes in hunger, fullness, and appetite-regulating hormones, the research aims to uncover how water intake influences weight loss.

Why it matters

Potential benefit: If successful, this research could provide a simple and effective strategy for older adults to manage their weight more effectively.

How similar studies have gone: Previous studies have shown promising results with premeal water consumption leading to reduced hunger and increased weight loss, suggesting this approach may be effective.

Where this research is happening

  • Virginia Polytechnic Inst and St Univ
    Blacksburg, United States
    Active

Researchers

  • Principal investigator: Davy, Brenda M — Virginia Polytechnic Inst and St Univ
  • Study coordinator: Davy, Brenda M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.