How dopamine signaling during sleep affects memory

The functions of dopamine signaling during sleep in memory

NIH-funded research University of Michigan at Ann Arbor · NIH-11021101

This study looks at how certain brain cells that use dopamine help us remember important experiences while we sleep, and it could lead to new ways to improve memory for people who have memory problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11021101 on NIH RePORTER

What this research studies

This research investigates the role of dopamine neurons in the brain during sleep and how they contribute to the formation of long-term memories from significant experiences. By examining the activity of these neurons, the study aims to understand how memories are consolidated during sleep, particularly focusing on the integration of dopamine signaling with other brain regions involved in memory. Patients may benefit from insights into how sleep and dopamine influence memory, potentially leading to new treatments for memory-related conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing memory issues or those interested in understanding the relationship between sleep and memory.

Not a fit: Patients with no memory concerns or those not experiencing significant sleep disturbances may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatments for memory disorders by highlighting the importance of sleep and dopamine in memory consolidation.

How similar studies have performed: Previous research has shown promising results regarding the role of dopamine in memory processes, suggesting that this approach could yield valuable insights.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.