How DNA modifications affect brain function and diseases
Dynamic DNA Modifications in Brain and Diseases
This study is looking at how changes in our DNA can affect brain development and contribute to conditions like memory issues and mental health disorders, helping us understand how these changes might impact you or your loved ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10927210 on NIH RePORTER |
What this research studies
This research investigates the role of epigenetic changes, specifically DNA modifications, in brain development and various neurological disorders. It focuses on how these modifications, such as cytosine methylation and its dynamic regulation, influence gene expression and cellular identity in the central nervous system. By exploring the plasticity of these modifications, the research aims to uncover their impact on learning, memory, and the development of neurodegenerative and psychiatric disorders. Patients may benefit from a deeper understanding of how these processes contribute to their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurodevelopmental, neurodegenerative, or psychiatric disorders linked to epigenetic changes.
Not a fit: Patients with conditions unrelated to epigenetic modifications or those without neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating neurodevelopmental and neurodegenerative disorders.
How similar studies have performed: Other research has shown promising results in understanding the role of epigenetics in brain function, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Jin, Peng — Emory University
- Study coordinator: Jin, Peng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.