How different ways of handling human milk affect its benefits for preterm infants

Effects of human milk handling practices on peptide release and bioactivity in the preterm infant intestine

NIH-funded research Oregon State University · NIH-10895389

This study looks at how different ways of storing and preparing breast milk, like freezing and heating, affect the good nutrients that help the intestines of premature babies, with the hope of finding the best feeding methods to support their health and growth in the NICU.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon State University NIH-funded
Lab location1 site (Corvallis, United States)
Project IDNIH-10895389 on NIH RePORTER

What this research studies

This research investigates how various handling practices of human milk, such as freezing and pasteurization, impact the release of beneficial peptides in the intestines of preterm infants. By analyzing the differences in milk sources and processing methods, the study aims to understand how these factors influence the bioactivity of milk peptides, which can play crucial roles in gut health and immune function. The goal is to identify optimal feeding practices that support the growth and development of preterm infants in the NICU.

Who could benefit from this research

Good fit: Ideal candidates for this research are preterm infants receiving human milk in a NICU setting.

Not a fit: Patients who are not preterm infants or those not receiving human milk will likely not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved feeding practices that enhance gut health and overall development in preterm infants.

How similar studies have performed: Other research has shown that handling practices can significantly affect the nutritional and bioactive properties of human milk, indicating a promising area of investigation.

Where this research is happening

Corvallis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.