How different types of lung cancer cells work together to invade tissues
Implications of metabolic heterogeneity on collective lung cancer cell invasion
This study is looking at how different types of lung cancer cells work together to spread and invade other parts of the body, using advanced technology to better understand their teamwork and how it affects cancer growth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11056830 on NIH RePORTER |
What this research studies
This research investigates how various sub-populations of lung cancer cells, which have different metabolic characteristics, cooperate to invade surrounding tissues and spread throughout the body. By isolating these specific cancer cell sub-populations, the study aims to understand their roles in tumor invasion and metastasis. The researchers utilize advanced imaging and genomics technology to analyze how these cells interact and function as a cohesive unit during the invasion process. This approach could reveal new insights into the mechanisms of lung cancer progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with lung adenocarcinoma who are interested in understanding the biological mechanisms of their cancer.
Not a fit: Patients with non-lung cancers or those who do not have adenocarcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for targeting lung cancer metastasis, potentially improving treatment outcomes for patients.
How similar studies have performed: While the investigation of metabolic heterogeneity in cancer is an emerging field, previous studies have shown promising results in understanding cancer cell behavior, indicating potential for success in this novel approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Shanmugam, Malathy (Mala) — Emory University
- Study coordinator: Shanmugam, Malathy (Mala)
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.