How different staphylococci affect skin health and disease
Official title: Molecular mechanisms of staphylococcal modulation of skin homeostasis
Funded at Duke University · NIH-11239508 · Data updated 2026-11-12
This study is looking at how different types of staph bacteria on our skin can affect skin health and conditions like eczema, and it invites patients to help by sharing skin samples to find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | February 10, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $653,018 |
| NIH project number | 7R01AR083742-02 |
| Project ID | NIH-11239508 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals with skin conditions like atopic dermatitis or allergic eczema.
✕Less likely to help
Patients with skin conditions unrelated to staphylococcal infections or those without any skin issues may not benefit from this research.
What this research studies
This research investigates the role of various staphylococcal species on skin health and disease. It focuses on understanding how these bacteria, which are common on human skin, can influence immune responses and skin barrier function. By examining the differences in staphylococcal strains found in healthy versus diseased skin, the study aims to uncover mechanisms that could lead to better treatments for conditions like eczema and other skin disorders. Patients may be involved in providing skin samples to help identify these bacterial interactions.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for skin conditions such as eczema and allergic dermatitis by targeting specific bacterial strains.
How similar studies have gone: Previous research has shown that understanding the skin microbiome can lead to significant advancements in treating skin diseases, suggesting this approach has potential for success.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Oh, Julia — Duke University
- Study coordinator: Oh, Julia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.