How different sides of the brain affect bladder pain processing
Impact of Amygdala Lateralization on Processing and Modulation of Bladder Pain
This study looks at how different parts of the brain affect bladder pain in people with chronic pelvic pain, hoping to find new ways to help ease their discomfort and improve their quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Dallas NIH-funded |
| Lab location | 1 site (Richardson, United States) |
| Project ID | NIH-10930918 on NIH RePORTER |
What this research studies
This research investigates how the left and right sides of the amygdala, a brain region involved in emotional processing, influence the experience of bladder pain in patients with urologic chronic pelvic pain syndrome (UCPPS). By using animal models, the study aims to understand the central nervous system's role in chronic pain and anxiety related to bladder conditions. The findings could help identify new treatment strategies that target these brain mechanisms to alleviate pain and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with urologic chronic pelvic pain syndrome (UCPPS) who experience persistent bladder pain.
Not a fit: Patients with acute bladder pain or those without a diagnosis of UCPPS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients suffering from chronic bladder pain.
How similar studies have performed: Previous research has shown that understanding brain mechanisms in pain processing can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
Richardson, United States
- University of Texas Dallas — Richardson, United States (Active)
Researchers
- Principal investigator: Kolber, Benedict J — University of Texas Dallas
- Study coordinator: Kolber, Benedict J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.