NIH-funded research R01 grant

How different parts of the brain work together to make decisions

Official title: Cross-brain, multi-region interactions in decision formation and decision commitment

Funded at Princeton University · NIH-11040135 · Data updated 2026-11-12

This study looks at how different parts of the brain work together when making decisions, using special tools to track the activity of many brain cells in rats as they move around freely, and it aims to help us understand more about how our brains think and behave.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPrinceton University
NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project startSeptember 18, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$823,252
NIH project number1R01MH138935-01
Project IDNIH-11040135 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research would be individuals with conditions affecting decision-making and cognitive function.

Less likely to help

Patients with isolated brain injuries or those not experiencing cognitive impairments may not benefit from this research.

What this research studies

This research investigates the interactions between various regions of the brain during decision-making processes. By using advanced techniques to record the activity of thousands of neurons simultaneously in freely-moving rats, the study aims to uncover how these brain regions communicate and influence each other. The researchers will also develop new analytical methods to interpret the complex data generated from these recordings, providing insights into the neural dynamics involved in cognition and behavior.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of brain function and lead to improved treatments for cognitive disorders.

How similar studies have gone: While there have been studies on single brain regions, this approach of simultaneous multi-region analysis is relatively novel and has not been extensively tested.

Where this research is happening

  • Princeton University
    Princeton, United States
    Active

Researchers

  • Principal investigator: Brody, Carlos D — Princeton University
  • Study coordinator: Brody, Carlos D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.