How different diets affect energy metabolism and body weight
Official title: Fluxomics Studies of the Effect of Diet Composition on Energy Metabolism
Funded at Harvard School of Public Health · NIH-11170808 · Data updated 2026-11-12
This study is looking at how different amounts of fats and carbohydrates in your diet affect how your body uses energy, helping you understand how your food choices can influence your weight and metabolism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $506,598 |
| NIH project number | 1R56DK140139-01 |
| Project ID | NIH-11170808 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals struggling with obesity or those interested in understanding how diet affects their metabolism.
✕Less likely to help
Patients who are not affected by obesity or those with metabolic disorders unrelated to diet may not benefit from this research.
What this research studies
This research investigates the impact of diet composition on energy metabolism, particularly focusing on how different levels of dietary fats and carbohydrates influence body weight and metabolic processes. By using advanced techniques like isotope tracer infusion, the study aims to quantify metabolic fluxes, which are the rates at which nutrients are processed in the body. This interdisciplinary approach seeks to fill knowledge gaps regarding the physiological mechanisms that link diet to obesity and related diseases. Patients may gain insights into how their dietary choices affect their metabolism and weight management.
Why it matters
Potential benefit: If successful, this research could lead to more effective dietary recommendations and interventions for obesity prevention and management.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between diet composition and metabolic processes, indicating that this approach could yield valuable insights.
Where this research is happening
-
Harvard School of Public Health
Boston, United States Active
Researchers
- Principal investigator: Hui, Sheng — Harvard School of Public Health
- Study coordinator: Hui, Sheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.