How dietary restriction affects aging differently in male and female invertebrates
Effects of dietary restriction in a new invertebrate model for sex-specific aging
['FUNDING_R03'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10629330
This study is looking at how changing what copepods eat can affect how long they live and how healthy they are, especially comparing males and females, to help us understand more about aging and longevity.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10629330 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of dietary restriction on aging in a new invertebrate model, the copepod Tigriopus californicus. It aims to understand how dietary changes can influence lifespan and health, particularly focusing on differences between male and female organisms. The study will explore the role of mitochondrial DNA variations and how they may affect the success of dietary interventions. By examining these factors, the research seeks to provide insights into the biological mechanisms of aging and longevity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of aging and those who may benefit from dietary interventions.
Not a fit: Patients with conditions unrelated to aging or dietary impacts may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary strategies that enhance lifespan and health in various organisms, potentially informing human health and aging.
How similar studies have performed: While dietary restriction has shown promise in extending lifespan across various species, this specific approach using copepods is novel and has not been extensively tested.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: EDMANDS, SUZANNE — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: EDMANDS, SUZANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: DNA Injury