How dietary L-Lysine affects kidney function and health

Transport and metabolism in the kidney

NIH-funded research James a. Haley VA Medical Center · NIH-10951492

This study is looking at how adding L-Lysine to your diet might help improve kidney health for people with high blood pressure and kidney problems by reducing stress and damage in kidney cells.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJames a. Haley VA Medical Center NIH-funded
Lab location1 site (Tampa, United States)
Project IDNIH-10951492 on NIH RePORTER

What this research studies

This research investigates the role of dietary L-Lysine in improving kidney function, particularly in the context of high blood pressure and kidney diseases. It aims to understand how L-Lysine supplementation can reduce metabolic stress and oxidative damage in kidney cells, potentially leading to better kidney health. The study uses animal models to explore the mechanisms by which L-Lysine influences kidney metabolism and the excretion of harmful substances. By examining these pathways, the research seeks to provide insights into dietary interventions that could benefit patients with chronic kidney conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with chronic kidney disease or hypertension who may benefit from dietary interventions.

Not a fit: Patients with acute kidney injury or those not experiencing metabolic disturbances related to kidney function may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations or treatments that improve kidney health and function in patients with hypertension and chronic kidney disease.

How similar studies have performed: Previous research has shown promising results with dietary interventions in kidney health, suggesting that this approach may yield beneficial outcomes.

Where this research is happening

Tampa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.