NIH-funded research NIH-funded research

How dietary L-Lysine affects kidney function and health

Official title: Transport and metabolism in the kidney

Funded at James a. Haley VA Medical Center · NIH-10951492 · Data updated 2026-11-12

This study is looking at how adding L-Lysine to your diet might help improve kidney health for people with high blood pressure and kidney problems by reducing stress and damage in kidney cells.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJames a. Haley VA Medical Center
NIH-funded
Lab location1 site (Tampa, United States)
Project startOctober 1, 2018
Project endSeptember 30, 2028
Funding year2025
NIH project number5I01BX004024-06
Project IDNIH-10951492 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with chronic kidney disease or hypertension who may benefit from dietary interventions.

Less likely to help

Patients with acute kidney injury or those not experiencing metabolic disturbances related to kidney function may not benefit from this research.

What this research studies

This research investigates the role of dietary L-Lysine in improving kidney function, particularly in the context of high blood pressure and kidney diseases. It aims to understand how L-Lysine supplementation can reduce metabolic stress and oxidative damage in kidney cells, potentially leading to better kidney health. The study uses animal models to explore the mechanisms by which L-Lysine influences kidney metabolism and the excretion of harmful substances. By examining these pathways, the research seeks to provide insights into dietary interventions that could benefit patients with chronic kidney conditions.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations or treatments that improve kidney health and function in patients with hypertension and chronic kidney disease.

How similar studies have gone: Previous research has shown promising results with dietary interventions in kidney health, suggesting that this approach may yield beneficial outcomes.

Where this research is happening

  • James a. Haley VA Medical Center
    Tampa, United States
    Active

Researchers

  • Principal investigator: Staruschenko, Alexander — James a. Haley VA Medical Center
  • Study coordinator: Staruschenko, Alexander

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.