How dietary fiber affects immune cells in the intestines
Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cells
This study is looking at how eating more fiber can change the bacteria in your gut and how that might help your immune system, especially for people with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11007383 on NIH RePORTER |
What this research studies
This research investigates the relationship between dietary fiber and the gut microbiome, focusing on how these factors influence the development and function of T cells in the small intestine. By examining the interactions between fiber intake and gut bacteria, the study aims to uncover mechanisms that could explain the impact of diet on inflammatory bowel diseases (IBD) like Crohn's disease and ulcerative colitis. The research employs a combination of dietary interventions and microbiome analysis to understand how changes in fiber consumption can alter immune responses in the intestines. This could lead to new dietary strategies for managing IBD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with inflammatory bowel diseases such as Crohn's disease or ulcerative colitis.
Not a fit: Patients without inflammatory bowel diseases or those who do not consume dietary fiber may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into dietary interventions that may help manage or prevent inflammatory bowel diseases.
How similar studies have performed: Previous research has indicated that dietary fiber can significantly influence gut health and immune responses, suggesting that this approach may yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Cervantes Barragan, Luisa — Emory University
- Study coordinator: Cervantes Barragan, Luisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.