How dietary fiber affects immune cells in the intestines
Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cells
This study is looking at how eating fiber affects the good bacteria in our gut and how that, in turn, helps our immune system work better, which could lead to new diet tips for people with inflammatory bowel disease (IBD).
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10891403 on NIH RePORTER |
What this research studies
This research investigates the interactions between dietary fiber and gut bacteria, focusing on how these interactions influence the development and function of immune cells in the small intestine. By examining the role of dietary fiber in shaping the microbiome, the study aims to uncover mechanisms that could lead to new dietary therapies for inflammatory bowel disease (IBD). The research utilizes a combination of animal models and microbiome analysis to explore how fiber intake impacts immune responses and inflammation in the gut. Patients may benefit from insights that could lead to personalized dietary recommendations for managing IBD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with inflammatory bowel disease, such as Crohn's disease or ulcerative colitis.
Not a fit: Patients without inflammatory bowel disease or those who do not consume dietary fiber may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new dietary strategies to help manage or prevent inflammatory bowel disease.
How similar studies have performed: Previous studies have shown promising results in understanding the role of diet and microbiome interactions in gut health, suggesting that this approach could lead to significant advancements in IBD treatment.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Cervantes Barragan, Luisa — Emory University
- Study coordinator: Cervantes Barragan, Luisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.