How dietary fats influence pancreatic cancer development
Official title: Dietary fatty acids drive pancreatic cancer development
Funded at Yale University · NIH-11043491 · Data updated 2026-11-12
This study is looking at how different types of fats in our diet, especially oleic acid, might influence the growth of pancreatic cancer, and it hopes to find helpful dietary tips that could lower cancer risk for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | July 10, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $183,977 |
| NIH project number | 3R01CA276108-02S1 |
| Project ID | NIH-11043491 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a high risk of pancreatic cancer, particularly those with obesity or a history of high-fat diet consumption.
✕Less likely to help
Patients who are not at risk for pancreatic cancer or those with other unrelated health conditions may not benefit from this research.
What this research studies
This research investigates the relationship between dietary fatty acids and the development of pancreatic cancer, specifically pancreatic ductal adenocarcinoma (PDAC). It aims to understand how different types of dietary fats, particularly oleic acid, affect tumor growth and progression. By using a controlled panel of high-fat diets that vary only in fat source, the study seeks to uncover the mechanisms by which these fats may promote cancer. Patients may benefit from insights that could lead to dietary recommendations aimed at reducing cancer risk.
Why it matters
Potential benefit: If successful, this research could lead to dietary guidelines that help reduce the risk of pancreatic cancer in at-risk populations.
How similar studies have gone: Previous research has shown that dietary factors can influence cancer development, but this specific approach focusing on the effects of different fatty acids on pancreatic cancer is relatively novel.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Muzumdar, Mandar Deepak — Yale University
- Study coordinator: Muzumdar, Mandar Deepak
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.