How dietary fats influence breast cancer in obese women
Dietary lipids as drivers and therapeutic targets in obesity-accelerated breast cancer
This study is looking at how the fats we eat might help breast cancer grow in women who are overweight, and it hopes to find new ways to treat this type of cancer by understanding how these cancer cells use fats for energy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10973832 on NIH RePORTER |
What this research studies
This research investigates how dietary lipids contribute to the growth of breast cancer in women with obesity. It aims to understand the metabolic changes that occur in breast cancer cells when exposed to high levels of dietary fats, as well as how these changes can be targeted for new treatments. The study will explore whether breast cancer cells prefer to use fats instead of sugars for energy in obese patients, and how this preference affects tumor growth. By identifying unique metabolic vulnerabilities in these cancer cells, the research seeks to develop more effective therapies for obesity-related breast cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women who are obese and diagnosed with breast cancer.
Not a fit: Patients who are not obese or do not have breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies that specifically target breast cancer in obese patients, potentially improving outcomes and survival rates.
How similar studies have performed: Other research has shown promising results in targeting metabolic pathways in cancer, suggesting that this approach could be effective.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Chaix, Amandine H. — University of Utah
- Study coordinator: Chaix, Amandine H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.