How dietary botanical supplements affect resilience to stress and behavior
Influence of Dietary Botanical Supplements on Biological and Behavioral Resilience
This study is looking at how certain plant-based supplements, especially those rich in polyphenols, can help people better cope with stress and reduce feelings of depression, and it's for anyone interested in natural ways to improve their mental health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10886088 on NIH RePORTER |
What this research studies
This research investigates the impact of dietary botanical supplements, particularly polyphenols, on biological and behavioral resilience against stress-induced psychological issues. Through a combination of pre-clinical and clinical approaches, the study aims to understand how these supplements can influence immune function and neuronal activity to promote resilience to stress. The research includes rigorous feasibility studies that have shown promising results in reducing depression-like behaviors in stress models. By identifying the bioavailable metabolites that affect inflammatory responses, the study seeks to establish a foundation for future clinical trials.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing stress-related psychological issues or those interested in dietary supplements for mental health.
Not a fit: Patients who do not experience stress-related conditions or who are not interested in dietary interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary interventions that enhance mental resilience and reduce the risk of stress-related psychological disorders.
How similar studies have performed: Previous studies have shown success in using dietary supplements to improve resilience against stress, indicating a promising avenue for further exploration.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Murrough, James Warren — Icahn School of Medicine at Mount Sinai
- Study coordinator: Murrough, James Warren
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.