How diet and inflammation are linked to Alzheimer's disease

The role of inflammation in the association between diet and Alzheimer's disease

NIH-funded research Columbia University Health Sciences · NIH-10533769

This study is looking at how different diets, especially Mediterranean-style eating, might help lower inflammation and reduce the risk of developing late-onset Alzheimer's disease in older adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10533769 on NIH RePORTER

What this research studies

This research investigates the connection between dietary patterns and the risk of developing late-onset Alzheimer's disease, focusing on the role of inflammation. By analyzing data from a diverse group of elderly individuals, the study aims to identify how specific diets, particularly Mediterranean-type diets, may reduce inflammation and, in turn, lower the risk of Alzheimer's. Researchers will measure various inflammatory markers to understand their relationship with dietary habits and cognitive health. The findings could lead to dietary recommendations that promote brain health in older adults.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults, particularly those at risk for Alzheimer's disease or experiencing early cognitive decline.

Not a fit: Patients who are not elderly or do not have risk factors for Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide insights into dietary changes that may help prevent or delay the onset of Alzheimer's disease.

How similar studies have performed: Previous studies have shown promising results linking diet and inflammation to cognitive health, suggesting that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.