NIH-funded research NIH-funded research

How diet affects inflammation and immunity in the gut

Official title: Dietary regulation of type 2 immunity and inflammation in the gut

Funded at Weill Medical Coll of Cornell Univ · NIH-11140814 · Data updated 2026-11-12

This study is looking at how the foods we eat, especially fiber, can affect our gut health and inflammation, with the goal of finding better ways to treat issues like inflammatory bowel disease and colorectal cancer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 10, 2023
Project endDecember 31, 2026
Funding year2025
Award (this year)$248,999
NIH project number4R00AI173660-03
Project IDNIH-11140814 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with gastrointestinal disorders such as inflammatory bowel disease or those at risk for colorectal cancer.

Less likely to help

Patients with gastrointestinal disorders not related to inflammation or those without dietary sensitivities may not benefit from this research.

What this research studies

This research investigates the impact of dietary factors, particularly dietary fiber, on gut health and inflammation. It aims to understand how the microbiota, which are the bacteria in our intestines, interact with dietary components to influence immune responses and inflammation-related diseases. By studying these interactions, the research seeks to uncover mechanisms that could lead to better treatments for conditions like inflammatory bowel disease and colorectal cancer. The approach includes examining how specific dietary components affect immune cells and gut health in experimental models.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary recommendations and therapies for patients suffering from gastrointestinal disorders.

How similar studies have gone: Previous research has shown promising results in understanding the role of diet and microbiota in gut health, indicating that this approach has potential for significant findings.

Where this research is happening

  • Weill Medical Coll of Cornell Univ
    New York, United States
    Active

Researchers

  • Principal investigator: Arifuzzaman, Mohammad — Weill Medical Coll of Cornell Univ
  • Study coordinator: Arifuzzaman, Mohammad

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.