How diet affects inflammation and healing in the intestines
Dietary Regulation of Intestinal Inflammation and Repair
This study is looking at how eating more fiber might help people with inflammatory bowel diseases, like ulcerative colitis and Crohn's disease, by seeing how it affects gut health and inflammation, which could lead to better treatments for these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11019845 on NIH RePORTER |
What this research studies
This research investigates the role of dietary components, particularly dietary fiber, in regulating intestinal inflammation and repair in patients with inflammatory bowel diseases (IBD) like ulcerative colitis and Crohn's disease. The study aims to understand how the microbiota, influenced by diet, can affect immune responses and potentially lead to new therapeutic targets for IBD. By analyzing the effects of a fiber-rich diet on immune cells in the colon, the research seeks to uncover mechanisms that could improve treatment options for patients suffering from these chronic conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with inflammatory bowel diseases, such as ulcerative colitis or Crohn's disease.
Not a fit: Patients without a diagnosis of inflammatory bowel diseases or those who do not have dietary restrictions related to fiber intake may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations and therapies that better manage inflammation and improve the quality of life for patients with IBD.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between diet and gut health, indicating that dietary interventions could be beneficial for managing IBD.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Artis, David — Weill Medical Coll of Cornell Univ
- Study coordinator: Artis, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.