How diet affects gut bacteria and survival in colorectal cancer patients

Role of the inflammatory dietary pattern in gut and colon tissue microbiomes and impact on survival outcomes among colorectal cancer patients

['FUNDING_R21'] · OHIO STATE UNIVERSITY · NIH-10947236

This study is looking at how what you eat, especially if it causes inflammation, affects the bacteria in your gut and how that might influence the progression of colorectal cancer and your overall health, so if you're a colorectal cancer patient, your dietary habits could help us learn more about this connection.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorOHIO STATE UNIVERSITY (nih funded)
Locations1 site (Columbus, UNITED STATES)
Trial IDNIH-10947236 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between dietary patterns, specifically inflammatory diets, and the gut microbiome in colorectal cancer (CRC) patients. By analyzing dietary habits and their impact on gut bacteria, the study aims to uncover how these factors influence cancer progression and patient survival. The research utilizes a novel scoring system to assess dietary inflammation and its correlation with tumor characteristics and patient outcomes. Patients may be asked to provide dietary information and undergo microbiome analysis to contribute to this important investigation.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with colorectal cancer who are willing to provide dietary information and participate in microbiome analysis.

Not a fit: Patients with colorectal cancer who are not willing to engage in dietary assessments or microbiome testing may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to dietary recommendations that improve survival outcomes for colorectal cancer patients.

How similar studies have performed: Previous research has indicated that dietary patterns can significantly influence cancer outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers, neoplasm/cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.