How diet affects fat and brain health in Alzheimer's disease

Dietary Effects on Imaging and Fluid-based Biomarkers of the Adipose-Brain Axis in Alzheimers Disease

NIH-funded research Wake Forest University Health Sciences · NIH-10606480

This study is looking at how what you eat and where your body stores fat might affect brain health in people with Alzheimer's, and it will explore if changing your diet can help improve things.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-10606480 on NIH RePORTER

What this research studies

This research investigates the relationship between dietary habits, adipose tissue (fat) distribution, and brain health in individuals with Alzheimer's disease. It aims to understand how changes in fat tissue can influence the progression of Alzheimer's and how dietary interventions might improve outcomes. The study will analyze biomarkers in cerebrospinal fluid to assess the impact of different diets on brain health and fat distribution. Participants may be involved in dietary interventions to explore these connections further.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing symptoms of Alzheimer's disease or are at risk for developing it.

Not a fit: Patients who are not experiencing cognitive decline or do not have a diagnosis related to Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to dietary recommendations that help slow the progression of Alzheimer's disease.

How similar studies have performed: Previous research has shown promising results in understanding the links between diet, obesity, and Alzheimer's disease, suggesting that this approach could yield valuable insights.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.