NIH-funded research R01 grant

How diet affects brain health and Alzheimer's disease in diverse populations

Official title: Dietary factors, neuroinflammation, plasma neurodegenerative biomarkers and Alzheimer’s disease in diverse cohorts

Funded at Rush University Medical Center · NIH-10985586 · Data updated 2026-11-12

This study is looking at how eating healthy foods might help keep our brains healthy and lower the risk of Alzheimer's disease, especially in different groups of people, and it involves sharing your eating habits and checking your brain health.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRush University Medical Center
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$787,390
NIH project number1R01AG085483-01A1
Project IDNIH-10985586 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include older adults from diverse backgrounds who are concerned about cognitive decline or have a family history of Alzheimer's disease.

Less likely to help

Patients with advanced Alzheimer's disease or those who are unable to provide dietary information may not benefit from this research.

What this research studies

This research investigates the impact of healthy diets on brain health and the risk of Alzheimer's disease (AD) in various populations. It aims to understand how dietary factors, such as antioxidants and essential fatty acids, influence neuroinflammation and the presence of biomarkers associated with AD. By studying these relationships, the research seeks to uncover the mechanisms that link diet to cognitive decline and AD pathology, particularly in underrepresented groups. Participants may provide dietary information and undergo assessments to evaluate their cognitive health and related biomarkers.

Why it matters

Potential benefit: If successful, this research could lead to dietary recommendations that help reduce the risk of Alzheimer's disease and improve cognitive health in diverse populations.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between diet and cognitive health, but this study focuses on diverse populations, making it a novel approach.

Where this research is happening

  • Rush University Medical Center
    Chicago, United States
    Active

Researchers

  • Principal investigator: Agarwal, Puja — Rush University Medical Center
  • Study coordinator: Agarwal, Puja

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.