How diet affects brain energy in aging and Alzheimer's disease
Official title: Investigating Neuroenergetic Changes through Diet in Aging and Alzheimer’s Disease (INC-AD)
Funded at University of Kansas Medical Center · NIH-10889811 · Data updated 2026-11-12
This study is looking at how following a ketogenic diet might help improve brain energy and function in older adults and those with Alzheimer's disease, using special imaging techniques to see how the diet affects brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | July 15, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $744,628 |
| NIH project number | 1R61AG087449-01 |
| Project ID | NIH-10889811 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults aged 21 and older who are experiencing cognitive decline or are at risk for Alzheimer's disease.
✕Less likely to help
Patients who are not experiencing cognitive decline or do not have a risk of Alzheimer's disease may not benefit from this research.
What this research studies
This research investigates how changes in diet, specifically the ketogenic diet, can influence brain energy metabolism in aging individuals and those with Alzheimer's disease. By utilizing advanced magnetic resonance spectroscopy techniques, the study aims to measure key biomarkers related to brain energy production and metabolism. Participants will be involved in a randomized clinical trial to assess the effects of the ketogenic diet on cognitive function and overall brain health. The goal is to better understand the mechanisms behind dietary impacts on brain energy and develop effective interventions for Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could lead to dietary interventions that significantly improve cognitive function and brain health in aging and Alzheimer's patients.
How similar studies have gone: Previous research has shown promising results with dietary interventions like the ketogenic diet in improving cognitive outcomes in Alzheimer's patients, suggesting a potential for success in this study.
Where this research is happening
-
University of Kansas Medical Center
Kansas City, United States Active
Researchers
- Principal investigator: Taylor, Matthew — University of Kansas Medical Center
- Study coordinator: Taylor, Matthew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.