How diabetes management affects the risk of Alzheimer's disease in older adults
Glycemic Control and Dementia: The Role of Pharmacotherapy and Vascular Complications
This study is looking at how managing diabetes might affect the chances of older adults developing Alzheimer's disease, using information from a large group of seniors with type 2 diabetes to help find ways to keep their brains healthy as they age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project ID | NIH-10766186 on NIH RePORTER |
What this research studies
This research investigates the relationship between diabetes management and the risk of developing Alzheimer's disease and related dementias in older adults. It utilizes a large database from the Kaiser Permanente Northern California Diabetes Registry, which includes data from over 115,000 elderly individuals with type 2 diabetes. The study aims to identify how long-term glycemic control and diabetes medications influence the risk of Alzheimer's disease, taking into account other health conditions that may affect outcomes. By understanding these factors, the research seeks to inform better clinical practices and interventions for healthy brain aging in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals aged 65 and older who have been diagnosed with type 2 diabetes.
Not a fit: Patients who do not have diabetes or are younger than 65 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing diabetes that may reduce the risk of Alzheimer's disease in older adults.
How similar studies have performed: Previous research has indicated a link between diabetes management and cognitive health, suggesting that this approach may yield valuable insights.
Where this research is happening
Oakland, UNITED STATES
- Kaiser Foundation Research Institute — Oakland, United States (Active)
Researchers
- Principal investigator: Gilsanz, Paola — Kaiser Foundation Research Institute
- Study coordinator: Gilsanz, Paola
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.